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Clinical Immunology | Class 2022

This year's Motto: Vaccines

Click for videos!

Prof. Eli C Lewis

Your cool TA: Dana

Quiz #1

Quiz #2

Quiz #3

Final exam 6/12/2018

24/7 Q&A*


*anonymous!

Set meeting with Lewis

Go to:

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Diseases you should know by now:

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Host defense: NADPH oxidase, catalase, oxidative burst, intracellular bacteria, extracellular bacteria, fungi, parasites, viruses, immune evasion, granuloma, dissemination

 Mega Quiz    

Di George Syndrome, tuberculosis infection, transplant rejection, acute (gut, skin) graft-versus-host disease, hypersensitivities I II III IV, allergies, transfusion reaction, Rh fetal hemolysis, myasthenia gravis, serum sickness, DTH, complement deficiencies, type 1 autoimmune diabetes, systemic lupus erythematosus (and associated nephropathy at times), IgA deficiency, multiple sclerosis, contact dermatitis, IL-12 receptor deficiency, Wisckot-Aldrich syndrome , can't believe I missed these but that's something you cannot say as an avid immuno follower!! -- RA and CGD

Lymph node, afferent/efferent, bone marrow, thymus, inflammation, self-limiting | Phagocyte, neutrophil, macrophage, monocyte, dendritic cell, T lymphocyte, T helper cell, B lymphocyte, HEV |  IL-1, IL-2, TNFa, IL-10, IL-8, MCP-1, CCR7

T zone  |  professional and non-professional antigen-presenting cells, IFNg, TCR, BCR, MHC class I, MHC class II, CD4, CD8, CD28/B7, CD40/CD40L, Fas/FasL, V(D)J recombination, activation, clonal expansion, immune memory | Germinal center, plasma cell, antibodies, isotype switching, somatic hypermutation, affinity maturation, FDCs

Thymic cortex and medulla (positive & negative selection), Central and peripheral immune tolerance, immune evasion  |  Cells types: Tregs, NK cells, M1- and M2-like macrophages  |  Cytokines: IL-10  |  Surface molecules: perforin

Germinal center, somatic hypermutation,plasma cell, IgM, IgG, IgA, IgE, mast cells, basophils, eosinophils, histamine, IgD and BCR, complement, C3 levels, MAC, neisseria meningitis and gonorhea

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Calendar

Your entire MSIH calendar

Bonus mateial

Bonus material

NETs

Neutrophil NETs and inflammation

Pregnancy & negotiations

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-  The End  -

Signaling lesson (insulin/glucagon biochem)

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TB meningitis

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Acquired Donor Peanut Allergy From Lung Transplantation Resulting in Respiratory Failure: A Case Report
Odish M, Chen M, Kim A, Floreth T
Abstract
This case report describes a patient who acquired a donor peanut allergy after lung transplantation. A 53-year-old woman with alpha-1 antitrypsin deficiency underwent left-sided lung transplant from a donor with a history of anaphylaxis to peanut. Two weeks after the transplant, the patient developed acute respiratory failure immediately after consuming a peanut butter and jelly sandwich. The donor's serum confirmed high titers of peanut-specific immunoglobulin E (IgE). The recipient patient had never had allergies to peanuts or other nuts before her transplant. After the transplant, she had negative serology but positive skin testing to peanuts. This case illustrates the importance of considering donor food allergies when caring for solid organ transplant recipients.

Transplant Proc. 2018 Aug 9. pii: S0041-1345(18)30776-0. doi: 10.1016/j.transproceed.2018.08.001. [Epub ahead of print]

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I LOVE IMMUNOLOGY!!! --->

Airborne contact dermatitis: common causes in the USA

Dessert
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